User blog comment:Plexioth- xD/Monster Hunter 3 Ultimate/@comment-5020152-20120913224745/@comment-4212769-20120913230425

Depends on what you want:

If you want to hunt only with friends or solo and want the 3D-effect you better get the 3DS version.

If you want to hunt online, with friends (they can also have the 3DS version to play with each other but again then local) or solo and want HD you better get WiiU version. (of course WiiU would cost more.)

Or just both if you have it and want it.