User blog comment:Plexioth- xD/Monster Hunter 3 Ultimate/@comment-28303251-20111024202356/@comment-76.69.5.128-20111024214351

Monster Hunter never got close to the limit of the UMD. Maybe this game will be bigger than a UMD, but it won't be the biggest 3DS ever.

Currently it looks like it will have 45-50 monsters and 250-300 quests... So it will probably be smaller than Freedom Unite (~60 monsters and ~400 quests.) I could be wrong. Hopefully it will still add a lot of new features, more interesting monsters, and other content.