User blog comment:PitchBlack696/Brute Tigrex/@comment-1784451-20101212053916/@comment-3347301-20110829143411

I don't think so, even on the quest "Monster Hunter" (I bet these were overpowered G-Level Monsters), with the Dark Akantor set (Defense 485 or something with Armourtalon), Tigrex could not 1-Hit KO me; it took away like 85-95 HP from me. Rathalos was much tougher. BTW I haven't even passed the quest yet. So, with Guardian Spirit Shin set (it says 570 defense fully upgraded without Armourtalon) you would hardly lose 60-65 HP xD I'd say, use Felyne meals or Max Potion etc.