User blog comment:Mckrongs/Monster Hunter 4 for the Nintendo 3DS/@comment-6050823-20130924212543/@comment-6050823-20130924222456

Nope, Guild House or Online only.

Also for any people wondering by what I mean by escaping, the monster will pretty much completely leave the Unknown Sea of Trees and go somewhere else if not enough damage is done in certain period of time(It actually adds a bit more realism in the game since all of the monsters only found in the Unknown Sea of Trees are rare). Another thing to note is that some random monsters that are not on the forecast will appear in the Unknown Sea of Trees after one of the monsters are killed, captured, or just escape so, you'll be still able to hunt monsters in it and random ones at that.